Hendrik Luesch Selected Research

Laxaphycin A

1/2018

Discovery of new A- and B-type laxaphycins with synergistic anticancer activity.

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Hendrik Luesch Research Topics

Disease

42	Neoplasms (Cancer) 01/2022 - 01/2002
8	Breast Neoplasms (Breast Cancer) 01/2021 - 08/2010
7	Colonic Neoplasms (Colon Cancer) 01/2022 - 03/2010
4	Colorectal Neoplasms (Colorectal Cancer) 03/2022 - 11/2011
4	Neoplasm Metastasis (Metastasis) 01/2021 - 09/2017
3	Triple Negative Breast Neoplasms 01/2021 - 11/2017
3	Hypoxia (Hypoxemia) 10/2018 - 01/2016
3	Neuroblastoma 04/2013 - 03/2007
2	Pancreatic Neoplasms (Pancreatic Cancer) 01/2021 - 01/2019
2	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2020 - 01/2008
2	Lung Diseases (Lung Disease) 01/2016 - 02/2013
2	Adenocarcinoma 08/2015 - 09/2010
2	Carcinoma (Carcinomatosis) 08/2015 - 09/2010
2	Inflammation (Inflammations) 09/2013 - 02/2013
1	Starvation 10/2021
1	Noncommunicable Diseases 09/2021
1	Pathologic Neovascularization 08/2021
1	Prostatic Neoplasms (Prostate Cancer) 01/2021
1	Colitis 01/2020
1	Opioid-Related Disorders (Opiate Addiction) 01/2020
1	Lung Neoplasms (Lung Cancer) 01/2020
1	Glioblastoma (Glioblastoma Multiforme) 01/2020
1	Brain Neoplasms (Brain Tumor) 01/2020
1	Central Nervous System Diseases (CNS Diseases) 01/2020
1	Choroidal Neovascularization 01/2019
1	Retinal Neovascularization 01/2019
1	Infections 10/2018
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2018

Drug/Important Bio-Agent (IBA)

8	largazoleIBA 08/2021 - 11/2010
7	Biological ProductsIBA 01/2021 - 04/2012
5	Pharmaceutical PreparationsIBA 10/2017 - 01/2011
4	Histone Deacetylases (Histone Deacetylase)IBA 08/2021 - 11/2010
4	Phosphotransferases (Kinase)IBA 10/2020 - 07/2009
4	Pancreatic Elastase (Elastase)IBA 01/2020 - 02/2013
4	Peptide Hydrolases (Proteases)FDA Link 07/2018 - 01/2016
3	Histone Deacetylase InhibitorsIBA 08/2021 - 11/2010
3	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2020 - 01/2011
3	apratoxin S10IBA 01/2019 - 10/2017
3	tyrosine receptor (receptor, tyrosine)IBA 01/2019 - 07/2009
3	Histones (Histone)IBA 08/2014 - 11/2010
3	apratoxin AIBA 11/2011 - 06/2008
2	ChromatinIBA 01/2022 - 03/2011
2	LuciferasesIBA 01/2022 - 03/2007
2	Proteasome Endopeptidase Complex (Proteasome)IBA 09/2021 - 01/2018
2	DepsipeptidesIBA 08/2021 - 02/2013
2	apratoxin S4IBA 01/2021 - 01/2019
2	TubulinIBA 01/2021 - 01/2020
2	Proteins (Proteins, Gene)FDA Link 01/2021 - 01/2008
2	Sulfhydryl Compounds (Thiols)IBA 01/2020 - 01/2017
2	RNA (Ribonucleic Acid)IBA 01/2020 - 01/2020
2	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2019 - 11/2011
2	Small Interfering RNA (siRNA)IBA 10/2018 - 11/2017
2	Anti-Bacterial Agents (Antibiotics)IBA 10/2018 - 01/2016
2	Cysteine (L-Cysteine)FDA Link 11/2017 - 06/2008
2	CathepsinsIBA 11/2017 - 01/2016
2	dolastatin 10IBA 03/2015 - 01/2002
2	symplostatin 1IBA 03/2015 - 04/2003
2	quinone (benzoquinone)IBA 04/2013 - 03/2007
2	Oxidoreductases (Dehydrogenase)IBA 04/2013 - 03/2007
2	NAD (NADH)IBA 04/2013 - 03/2007
2	Sunitinib (Sutent)FDA Link 09/2011 - 01/2011
2	Bevacizumab (Avastin)FDA Link 09/2011 - 01/2011
2	Sorafenib (BAY 43-9006)FDA Link 09/2011 - 01/2011
1	Carboxylic AcidsIBA 03/2022
1	dysidazirineIBA 03/2022
1	IronIBA 10/2021
1	AlkaloidsIBA 09/2021
1	aaptamineIBA 09/2021
1	homoserine lactoneIBA 01/2021
1	AndrogensIBA 01/2021
1	Brain-Derived Neurotrophic Factor (BDNF)IBA 01/2020
1	ProdrugsIBA 01/2020
1	dolastatin 15IBA 01/2020
1	VincamineIBA 01/2020
1	CalciumIBA 01/2020
1	Yohimbine (Yocon)IBA 01/2020
1	LipocalinsIBA 01/2020
1	Antineoplastic Agents (Antineoplastics)IBA 01/2019
1	CytokinesIBA 01/2019
1	Oxygen (Dioxygen)IBA 01/2019
1	Thiamine (Aneurin)FDA Link 10/2018
1	Kallikreins (Kallikrein)IBA 07/2018
1	Serine Proteases (Serine Protease)IBA 07/2018
1	Dihydrotachysterol (AT 10)IBA 07/2018
1	Cardiac GlycosidesIBA 01/2018
1	molassamideIBA 01/2018
1	UbiquitinIBA 01/2018
1	Peptides (Polypeptides)IBA 01/2018
1	Laxaphycin AIBA 01/2018
1	Plasminogen Activator Inhibitor 1IBA 11/2017
1	Biomarkers (Surrogate Marker)IBA 11/2017
1	Cystatin CIBA 11/2017
1	grassystatin FIBA 11/2017
1	Cathepsin DIBA 11/2017
1	Protease Inhibitors (Protease Inhibitor)IBA 11/2017
1	Interleukin-6 (Interleukin 6)IBA 10/2017
1	Vascular Endothelial Growth Factor Receptor-2 (Vascular Endothelial Growth Factor Receptor 2)IBA 10/2017

Therapy/Procedure

11	Therapeutics 01/2022 - 11/2010
2	Drug Therapy (Chemotherapy) 01/2021 - 01/2018
1	Lasers (Laser) 01/2019